The name is derived from the Lithuanian hydronym Alytupis.
The first historical record of Alytus dates back to 1377, when it was mentioned in the Chronicles of Wigand of Marburg under the name of Aliten.
Alytus has a humid continental climate with quite large seasonal differences.
Alytus has a museum dedicated to veterans of both the Afghan wars.
Alytus hosted the Art Strike Biennial between 18 and 24 August 2009 in response to Vilnius becoming European Capital of Culture for 2009.
Alytus has hosted an annual Tomato tasting since 2007.
On 15 June 1581 Grand Duke of Lithuania and King of Poland Stefan Batory granted the town the city rights based on the Magdeburg Law. The event is celebrated as the Alytus Day.